KLF6 anticorps (N-Term)

N° du produit ABIN2776378

Détail du produit anti-KLF6 anticorps

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF6 est non-conjugé

Application: Western Blotting (WB)

Séquence: REKKEESELK ISSSPPEDTL ISPSFCYNLE TNSLNSDVSS ESSDSSEELS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against KLF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 283 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLF6

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Autre désignation: KLF6 (KLF6 Produits)

Synonymes: anticorps gbf, anticorps zf9, anticorps bcd1, anticorps cba1, anticorps cpbp, anticorps pac1, anticorps st12, anticorps copeb, anticorps MGC53475, anticorps KLF6, anticorps MGC127307, anticorps BCD1, anticorps CBA1, anticorps COPEB, anticorps CPBP, anticorps GBF, anticorps PAC1, anticorps ST12, anticorps ZF9, anticorps AI448727, anticorps C86813, anticorps Copeb, anticorps FM2, anticorps FM6, anticorps Ierepo1, anticorps Ierepo3, anticorps R75280, anticorps Zf9, anticorps Aa1017, anticorps klf6, anticorps cb538, anticorps wu:fb76d04, anticorps wu:fb92h03, anticorps wu:fe26g06, anticorps wu:fk78f12, anticorps Kruppel-like factor 6 L homeolog, anticorps Kruppel like factor 6, anticorps Krueppel-like factor 6, anticorps Kruppel-like factor 6, anticorps Kruppel-like factor 6 S homeolog, anticorps Kruppel-like factor 6a, anticorps klf6.L, anticorps KLF6, anticorps LOC100196412, anticorps klf6, anticorps Klf6, anticorps klf6.S, anticorps klf6a

Sujet: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-731 BM544849.1 20-750 732-1504 BC000311.2 669-1441 1505-1598 BC004301.1 1440-1533
Alias Symbols: BCD1, COPEB, CPBP, DKFZp686N0199, GBF, PAC1, ST12, ZF9, CBA1
Protein Interaction Partner: UBC, APP, LCOR, SP1, NUFIP1, NOP56, TAF9, FBL, HDAC3, E2F1, NR0B2, PNO1, POLA2, GTF3C1, EHMT2, APOM, CELSR2, KLF4, TP53, CCND1,
Protein Size: 283

Poids moléculaire: 32 kDa

ID gène: 1316

NCBI Accession: NM_001300, NP_001291

UniProt: Q99612