EED anticorps (N-Term)

N° du produit ABIN2776407

Détail du produit anti-EED anticorps

Antigène: EED (Embryonic Ectoderm Development (EED))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EED est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: GDENDDAVSI ESGTNTERPD TPTNTPNAPG RKSWGKGKWK SKKCKYSFKC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against EED. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EED

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 441 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EED (ABIN2776407)

Lin, Huang, Chang, Chang, Yen, Lee, Chang, Liu, Chang: "Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2." dans: BMC cancer, Vol. 16, pp. 583, (2016) (PubMed).

Rakotobe, Violot, Hong, Gouet, Boulanger: "Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED." dans: Virology journal, Vol. 5, pp. 32, (2008) (PubMed).

Détails sur EED

Antigène: EED (Embryonic Ectoderm Development (EED))

Autre désignation: EED (EED Produits)

Synonymes: anticorps Xeed, anticorps heed, anticorps wait1, anticorps EED, anticorps HEED, anticorps WAIT1, anticorps zgc:112509, anticorps Xeed-B, anticorps eed, anticorps psXEED, anticorps ENSMUSG00000039373, anticorps l(7)5Rn, anticorps l7Rn5, anticorps lusk, anticorps Xeed-A, anticorps embryonic ectoderm development, anticorps embryonic ectoderm development S homeolog, anticorps microRNA 6755, anticorps embryonic ectoderm development L homeolog, anticorps eed, anticorps EED, anticorps eed.S, anticorps MIR6755, anticorps Eed, anticorps eed.L

Sujet: EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhance
Alias Symbols: HEED, WAIT1
Protein Interaction Partner: PINK1, BRCA1, ADAM17, EZH2, IMP3, PSPC1, NAT10, PBRM1, RIF1, RBM28, HEATR1, MAGOHB, ARGLU1, MRPL20, NRDE2, CASZ1, BCOR, EXOSC4, LUC7L3, SF3B6, NOP58, SRRT, RAB14, C9orf114, CRNKL1, DDX47, HP1BP3, MYEF2, TRA2A, CPSF1, IGHV3-23, UTP20, PRPF19, ZNF638, RBMX,
Protein Size: 441

Poids moléculaire: 50 kDa

ID gène: 8726

NCBI Accession: NM_003797, NP_003788

UniProt: O75530