NMI anticorps (Middle Region)

N° du produit ABIN2776425

Cet anticorps Lapin Polyclonal détecte spécifiquement NMI dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Cobaye et Cheval.

Aperçu rapide pour NMI anticorps (Middle Region) (ABIN2776425)

Antigène: NMI (N-Myc (And STAT) Interactor (NMI))

Reactivité: Humain, Rat, Souris, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMI est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NMI anticorps

Épitope: Middle Region

Séquence: SFSKSRNGGG EVDRVDYDRQ SGSAVITFVE IGVADKILKK KEYPLYINQT

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NMI. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NMI

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 307 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NMI

Antigène: NMI (N-Myc (And STAT) Interactor (NMI))

Autre désignation: NMI

Sujet: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: HSPA8, GCSH, GOLGA8EP, HDDC3, C9orf72, TXLNA, TXLNB, CNKSR3, LCA5L, C1orf216, SFR1, TUBA3E, MTMR9, COPS7B, BRMS1, KDM1A, POMZP3, HHLA3, EMILIN1, SNAPC5, MAD2L1BP, NMI, MTMR6, SCEL, TRAF5, UBC, PSMG3, OXR1, EXOSC4, TOLLIP, CYHR1, VPS26A, H1FX, NAA10, TBCD,
Protein Size: 307

Poids moléculaire: 35 kDa

ID gène: 9111

NCBI Accession: NM_004688, NP_004679

UniProt: Q13287