MAGEA9 anticorps (Middle Region)

N° du produit ABIN2776439

Cet anticorps Lapin Polyclonal détecte spécifiquement MAGEA9 dans WB. Il présente une réactivité envers Humain, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Porc et Saccharomyces cerevisiae.

Aperçu rapide pour MAGEA9 anticorps (Middle Region) (ABIN2776439)

Antigène: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Reactivité: Humain, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGEA9 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAGEA9 anticorps

Épitope: Middle Region

Séquence: ALKLKVAELV HFLLHKYRVK EPVTKAEMLE SVIKNYKRYF PVIFGKASEF

Homologie: Cow: 77%, Dog: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rabbit: 85%, Rat: 85%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against MAGEA9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 315 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAGEA9

Antigène: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Autre désignation: MAGEA9

Sujet: MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Alias Symbols: MAGE9, MGC8421, CT1.9, MAGEA9B
Protein Interaction Partner: APPL1, UBC, EGLN1,
Protein Size: 315

Poids moléculaire: 35 kDa

ID gène: 4108

NCBI Accession: NM_005365, NP_005356

UniProt: P43362