NCOA4 anticorps (C-Term)
Aperçu rapide pour NCOA4 anticorps (C-Term) (ABIN2776441)
Antigène
Voir toutes NCOA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- KEVPGTEDRA GKQKFKSPMN TSWCSFNTAD WVLPGKKMGN LSQLSSGEDK
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Homologie
- Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against NCOA4. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 614 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))
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Autre désignation
- NCOA4
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Sujet
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This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.
Alias Symbols: ARA70, DKFZp762E1112, ELE1, PTC3, RFG
Protein Interaction Partner: UBC, AR, RXRA, ATXN2, AKT1, VDR, GTF2B, KAT2B, RNF14, PPARG, NR3C1, ESR1,
Protein Size: 614 -
Poids moléculaire
- 70 kDa
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ID gène
- 8031
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NCBI Accession
- NM_005437, NP_005428
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UniProt
- Q13772
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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