SSX4 anticorps (N-Term)

N° du produit ABIN2776445

L’anticorps anti-SSX4 Polyclonal Lapin est utilisé pour la détection de SSX4 dans des échantillons de Humain et Boeuf (Vache). Il a été validé pour WB.

Aperçu rapide pour SSX4 anticorps (N-Term) (ABIN2776445)

Antigène: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSX4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SSX4 anticorps

Épitope: N-Term

Fonction: SSX4 Antibody - N-terminal region

Séquence: NGDDAFARRP RDDAQISEKL RKAFDDIAKY FSKKEWEKMK SSEKIVYVYM

Homologie: Cow: 83%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SSX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SSX4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35782-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SSX4

Antigène: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Autre désignation: SSX4

Sujet:

Background Information: SSX4 belongs to the SSX family. It contains 1 KRAB-related domain.SSX4 could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Synovial sarcoma, X breakpoint 4

Alternative Symbols: CT5.4

Protein Name: Protein SSX4

Poids moléculaire: 22kDa

ID gène: 6759

NCBI Accession: NP_005627

UniProt: O60224