PCBP4 anticorps (C-Term)

N° du produit ABIN2776535

L’anticorps anti-PCBP4 Polyclonal Lapin est utilisé pour la détection de PCBP4 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour PCBP4 anticorps (C-Term) (ABIN2776535)

Antigène: PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCBP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCBP4 anticorps

Épitope: C-Term

Fonction: PCBP4 Antibody - C-terminal region

Séquence: QTSSQEFLVP NDLIGCVIGR QGSKISEIRQ MSGAHIKIGN QAEGAGERHV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCBP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PCBP4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108475

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCBP4

Antigène: PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

Autre désignation: PCBP4

Sujet:

Background Information: PCBP4 is a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

Gene Name: Poly(rC) binding protein 4

Alternative Symbols: CBP, LIP4, MCG10

Protein Name: Poly(RC) binding protein 4, isoform CRA_a EMBL EAW65165.1

Poids moléculaire: 47kDa

ID gène: 57060

NCBI Accession: NP_065151

UniProt: Q9GZT1