FIP1L1 anticorps (C-Term)

N° du produit ABIN2776582

Détail du produit anti-FIP1L1 anticorps

Antigène: FIP1L1 (FIP1 Like 1 (FIP1L1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIP1L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EYAERGYERH RASREKEERH RERRHREKEE TRHKSSRSNS RRRHESEEGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FIP1L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FIP1L1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 594 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FIP1L1

Antigène: FIP1L1 (FIP1 Like 1 (FIP1L1))

Autre désignation: FIP1L1 (FIP1L1 Produits)

Synonymes: anticorps FIP1, anticorps Rhe, anticorps hFip1, anticorps 1300019H17Rik, anticorps Rje, anticorps fip1l1, anticorps wu:fd36f11, anticorps zgc:103421, anticorps factor interacting with PAPOLA and CPSF1, anticorps factor interacting with PAPOLA and CPSF1 S homeolog, anticorps FIP1 like 1 (S. cerevisiae), anticorps FIP1 like 1b (S. cerevisiae), anticorps fip1l1, anticorps FIP1L1, anticorps fip1l1.S, anticorps Fip1l1, anticorps fip1l1b

Sujet: FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
Alias Symbols: DKFZp586K0717, FLJ33619, Rhe, hFip1
Protein Interaction Partner: ZMYND19, CPSF4, NAA10, SGTA, GOLGA2, STAU1, UBC, WWOX, SUZ12, RNF2, EZH2, PRMT6, PRMT2, CLK2, HDAC9, CSNK2A1, LIG4, WDR33, CPSF2, CPSF3, CPSF1, NUP153, APP, COPS5, HNRNPA1, SRRM2, RNPS1,
Protein Size: 594

Poids moléculaire: 65 kDa

ID gène: 81608

NCBI Accession: NM_030917, NP_112179

UniProt: Q6UN15