CELF6 anticorps (Middle Region)

N° du produit ABIN2776609

Détail du produit anti-CELF6 anticorps

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELF6 est non-conjugé

Application: Western Blotting (WB)

Séquence: QAALLAAAQG PGLGPVAAVA AQMQHVAAFS LVAAPLLPAA AANSPPGSGP

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BRUNOL6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 481 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CELF6

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Autre désignation: BRUNOL6 (CELF6 Produits)

Synonymes: anticorps BRUNOL6, anticorps 6330569O16Rik, anticorps Brunol6, anticorps CUGBP Elav-like family member 6, anticorps CUGBP, Elav-like family member 6, anticorps CELF6, anticorps Celf6

Sujet: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.
Alias Symbols: CELF6, BRUNOL6
Protein Size: 481

Poids moléculaire: 50 kDa

ID gène: 60677

NCBI Accession: NM_052840, NP_443072

UniProt: Q96J87