CELF6 anticorps (Middle Region)

N° du produit ABIN2776609

Cet anticorps anti-CELF6 Polyclonal Lapin (ABIN2776609) détecte spécifiquement CELF6 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour CELF6 anticorps (Middle Region) (ABIN2776609)

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CELF6 anticorps

Épitope: Middle Region

Fonction: BRUNOL6 Antibody - middle region

Séquence: QAALLAAAQG PGLGPVAAVA AQMQHVAAFS LVAAPLLPAA AANSPPGSGP

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BRUNOL6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human BRUNOL6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41078-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CELF6

Antigène: CELF6 (CUGBP, Elav-Like Family Member 6 (CELF6))

Autre désignation: BRUNOL6

Sujet:

Background Information: BRUNOL6 is a RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. It mediates exon inclusion and/or exclusion in pre-mRNAs that are subject to tissue-specific and developmentally regulated alternative splicing. BRUNOL6 specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. It also promotes exon exclusion of INSR pre-mRNA.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.

Gene Name: CUGBP, Elav-like family member 6

Alternative Symbols: BRUNOL6

Protein Name: CUGBP Elav-like family member 6

Poids moléculaire: 50kDa

ID gène: 60677

NCBI Accession: NP_443072

UniProt: Q96J87