TPM3 anticorps (Middle Region)

N° du produit ABIN2776646

Cet anticorps anti-TPM3 est un anticorps Lapin Polyclonal détectant TPM3 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour TPM3 anticorps (Middle Region) (ABIN2776646)

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPM3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPM3 anticorps

Épitope: Middle Region

Séquence: TEERAELAES RCREMDEQIR LMDQNLKCLS AAEEKYSQKE DKYEEEIKIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TPM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TPM3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 285 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TPM3 (ABIN2776646)

Ramsey, Clarke, Roberts, Sullivan, Johnson, Liu: "An economic evaluation of atorvastatin for primary prevention of cardiovascular events in type 2 diabetes." dans: PharmacoEconomics, Vol. 26, Issue 4, pp. 329-39, (2008) (PubMed).

Détails sur TPM3

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Autre désignation: TPM3

Sujet: TPM3 is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer.This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ41118, MGC14582, MGC3261, MGC72094, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TPMsk3, TRK, hscp30, TM5, CFTD, hTM5
Protein Interaction Partner: TLK1, MAD1L1, TRIP6, TPM3, TP53, TNNT1, VPS52, TRIM27, PBX3, MAGEA11, KIFC3, KCNE1, IFIT3, HSF2, LURAP1, WASH3P, HDDC3, FAM9C, LCA5L, C1orf216, IKBIP, SYCE1, CCDC114, CCDC102B, KXD1, CCDC146, THAP1, CCHCR1, TFPT, BLOC1S6, OIP5, UBC, MDM2, RNF2, MAGED2, MG
Protein Size: 285

Poids moléculaire: 33 kDa

ID gène: 7170

NCBI Accession: NM_153649, NP_705935

UniProt: P06753