TPM3 anticorps (Middle Region)

N° du produit ABIN2776646

Cité dans 1 publication. Cet anticorps anti-TPM3 Polyclonal Lapin (ABIN2776646) détecte spécifiquement TPM3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour TPM3 anticorps (Middle Region) (ABIN2776646)

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPM3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPM3 anticorps

Épitope: Middle Region

Fonction: TPM3 Antibody - middle region

Séquence: TEERAELAES RCREMDEQIR LMDQNLKCLS AAEEKYSQKE DKYEEEIKIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TPM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TPM3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41141-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TPM3 (ABIN2776646)

Ramsey, Clarke, Roberts, Sullivan, Johnson, Liu: "An economic evaluation of atorvastatin for primary prevention of cardiovascular events in type 2 diabetes." dans: PharmacoEconomics, Vol. 26, Issue 4, pp. 329-39, (2008) (PubMed).

Détails sur TPM3

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Autre désignation: TPM3

Sujet:

Background Information: TPM3 is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer.This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Tropomyosin 3

Alternative Symbols: TM3, TM5, TRK, CFTD, NEM1, TM-5, TM30, CAPM1, TM30nm, TPM3nu, TPMsk3, hscp30, HEL-189, HEL-S-82p, OK/SW-cl.5

Protein Name: Tropomyosin alpha-3 chain

Poids moléculaire: 33kDa

ID gène: 7170

NCBI Accession: NP_705935

UniProt: P06753