DCP2 anticorps (C-Term)

N° du produit ABIN2776652

Cet anticorps Lapin Polyclonal détecte spécifiquement DCP2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Chien, Cheval, Porc et Boeuf (Vache).

Aperçu rapide pour DCP2 anticorps (C-Term) (ABIN2776652)

Antigène: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Reactivité: Humain, Souris, Rat, Cobaye, Chien, Cheval, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCP2 anticorps

Épitope: C-Term

Séquence: VEKLSRTKFR HSQQLFPDGS PGDQWVKHRQ PLQQKPYNNH SEMSDLLKGK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DCP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 420 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCP2

Antigène: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Autre désignation: DCP2

Sujet: DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
Alias Symbols: FLJ33245, NUDT20
Protein Interaction Partner: FAM96B, DCP1A, UBC, EDC4, DCP1B, SFXN2, ANGEL2, ARMCX5, DARS2, ELP3, QPCTL, GTPBP2, TRMT2A, FBXO3, INTS7, POLD3, GFPT2, AP1M1, SQSTM1, IKBKAP, TRRAP, TARS, ABCE1, PHKB, PGM3, PFKM, IDE, GLUD1, GGT7, GGCX, GFPT1, GARS, FANCD2, EIF5A, SLC25A10, CAPN2, NAGK,
Protein Size: 420

Poids moléculaire: 48 kDa

ID gène: 167227

NCBI Accession: NM_152624, NP_689837

UniProt: Q8IU60