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DCP2 anticorps (C-Term)

DCP2 Reactivité: Humain, Souris, Rat, Cobaye, Porc, Chien, Cheval, Boeuf (Vache) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776652
  • Antigène Voir toutes DCP2 Anticorps
    DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
    Épitope
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 40
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Cobaye, Porc, Chien, Cheval, Boeuf (Vache)
    Hôte
    • 37
    • 3
    Lapin
    Clonalité
    • 39
    • 1
    Polyclonal
    Conjugué
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DCP2 est non-conjugé
    Application
    • 27
    • 19
    • 17
    • 14
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VEKLSRTKFR HSQQLFPDGS PGDQWVKHRQ PLQQKPYNNH SEMSDLLKGK
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human DCP2
    Top Product
    Discover our top product DCP2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 420 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
    Autre désignation
    DCP2 (DCP2 Produits)
    Synonymes
    anticorps DDBDRAFT_0185453, anticorps DDBDRAFT_0252811, anticorps DDB_0185453, anticorps DDB_0252811, anticorps 2410015D23Rik, anticorps 5730537H01Rik, anticorps AL118268, anticorps NUDT20, anticorps RGD1562909, anticorps mRNA-decapping enzyme 2, anticorps hypothetical protein, anticorps decapping mRNA 2, anticorps CpipJ_CPIJ019463, anticorps PTRG_05936, anticorps dcp2, anticorps MCYG_05106, anticorps MGYG_07617, anticorps PGTG_03310, anticorps Tsp_04018, anticorps DCP2, anticorps Dcp2
    Sujet
    DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
    Alias Symbols: FLJ33245, NUDT20
    Protein Interaction Partner: FAM96B, DCP1A, UBC, EDC4, DCP1B, SFXN2, ANGEL2, ARMCX5, DARS2, ELP3, QPCTL, GTPBP2, TRMT2A, FBXO3, INTS7, POLD3, GFPT2, AP1M1, SQSTM1, IKBKAP, TRRAP, TARS, ABCE1, PHKB, PGM3, PFKM, IDE, GLUD1, GGT7, GGCX, GFPT1, GARS, FANCD2, EIF5A, SLC25A10, CAPN2, NAGK,
    Protein Size: 420
    Poids moléculaire
    48 kDa
    ID gène
    167227
    NCBI Accession
    NM_152624, NP_689837
    UniProt
    Q8IU60
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