DCP2 anticorps (C-Term)
-
- Antigène Voir toutes DCP2 Anticorps
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat, Cobaye, Porc, Chien, Cheval, Boeuf (Vache)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DCP2 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- VEKLSRTKFR HSQQLFPDGS PGDQWVKHRQ PLQQKPYNNH SEMSDLLKGK
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against DCP2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DCP2
- Top Product
- Discover our top product DCP2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 420 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
- Autre désignation
- DCP2 (DCP2 Produits)
- Synonymes
- anticorps DDBDRAFT_0185453, anticorps DDBDRAFT_0252811, anticorps DDB_0185453, anticorps DDB_0252811, anticorps 2410015D23Rik, anticorps 5730537H01Rik, anticorps AL118268, anticorps NUDT20, anticorps RGD1562909, anticorps mRNA-decapping enzyme 2, anticorps hypothetical protein, anticorps decapping mRNA 2, anticorps CpipJ_CPIJ019463, anticorps PTRG_05936, anticorps dcp2, anticorps MCYG_05106, anticorps MGYG_07617, anticorps PGTG_03310, anticorps Tsp_04018, anticorps DCP2, anticorps Dcp2
- Sujet
-
DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly(A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-539 AY135173.1 1-539 540-1992 AK090564.1 481-1933 1993-8947 AC008536.7 154323-161277
Alias Symbols: FLJ33245, NUDT20
Protein Interaction Partner: FAM96B, DCP1A, UBC, EDC4, DCP1B, SFXN2, ANGEL2, ARMCX5, DARS2, ELP3, QPCTL, GTPBP2, TRMT2A, FBXO3, INTS7, POLD3, GFPT2, AP1M1, SQSTM1, IKBKAP, TRRAP, TARS, ABCE1, PHKB, PGM3, PFKM, IDE, GLUD1, GGT7, GGCX, GFPT1, GARS, FANCD2, EIF5A, SLC25A10, CAPN2, NAGK,
Protein Size: 420 - Poids moléculaire
- 48 kDa
- ID gène
- 167227
- NCBI Accession
- NM_152624, NP_689837
- UniProt
- Q8IU60
-