WDR4 anticorps (C-Term)
Aperçu rapide pour WDR4 anticorps (C-Term) (ABIN2776747)
Antigène
Voir toutes WDR4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- AGADASFSSL YKATFDNVTS YLKKKEERLQ QQLEKKQRRR SPPPGPDGHA
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Homologie
- Cow: 93%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 90%, Rabbit: 83%, Rat: 75%, Yeast: 75%
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Attributs du produit
- This is a rabbit polyclonal antibody against WDR4. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 412 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WDR4 (WD Repeat Domain 4 (WDR4))
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Autre désignation
- WDR4
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Sujet
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WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: TRM82
Protein Interaction Partner: FAM118A, RABGGTB, METTL1, LGR4, CUL5, PDE12, WDR92, DCTPP1, P3H1, ELAC2, XPO5, NPLOC4, UBE2R2, DPP8, PPME1, ERO1L, UBQLN2, DBNL, KIAA1279, ARIH1, HSPBP1, PLIN3, ACTR2, SAE1, ASMTL, OGT, SURF2, SRP14, DNAJB1, DDX5, ALAD, ADSL, ERC1, UBP1, UBE2D1, TERF2, TE
Protein Size: 412 -
Poids moléculaire
- 45 kDa
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ID gène
- 10785
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NCBI Accession
- NM_033661, NP_387510
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UniProt
- P57081
Antigène
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