ADAM12 anticorps (N-Term)

N° du produit ABIN2776751

Cet anticorps Lapin Polyclonal détecte spécifiquement ADAM12 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour ADAM12 anticorps (N-Term) (ABIN2776751)

Antigène: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADAM12 anticorps

Épitope: N-Term

Séquence: VELVIVADNR EFQRQGKDLE KVKQRLIEIA NHVDKFYRPL NIRIVLVGVE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ADAM12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 909 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADAM12

Antigène: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Autre désignation: ADAM12

Sujet: ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
Alias Symbols: MCMP, MCMPMltna, MLTN, MLTNA
Protein Interaction Partner: SH3D19, PACSIN3, FSTL3, SRC, PIK3R1, YES1, IGFBP5, IGFBP3, EGF, GRB2, ACTN2,
Protein Size: 909

Poids moléculaire: 100 kDa

ID gène: 8038

NCBI Accession: NM_021641, NP_067673

UniProt: O43184

Pathways: EGFR Signaling Pathway