FBLN3 anticorps (Middle Region)
Aperçu rapide pour FBLN3 anticorps (Middle Region) (ABIN2776756)
Antigène
Voir toutes FBLN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- KYMSIRSDRS VPSDIFQIQA TTIYANTINT FRIKSGNENG EFYLRQTSPV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against EFEMP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human EFEMP1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 493 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." dans: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).
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: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." dans: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).
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- FBLN3 (Fibulin 3 (FBLN3))
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Autre désignation
- EFEMP1
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Sujet
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EFEMP1 gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
Alias Symbols: DHRD, DRAD, FBLN3, FBNL, FLJ35535, MGC111353, MLVT, MTLV, S1-5
Protein Interaction Partner: TXNDC5, RIC8A, BAG6, TRAF2, SGTA, env, HCVgp1, KHDRBS1, TNIP1, SOCS6, UBC, PDIA3, NOS3, GFI1B, ATN1, RERE, ATXN7, CACNA1A, ARAF, TIMP3, RAF1,
Protein Size: 493 -
Poids moléculaire
- 53 kDa
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ID gène
- 2202
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NCBI Accession
- NM_004105, NP_004096
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UniProt
- Q12805
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Pathways
- EGFR Signaling Pathway
Antigène
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