ELAC2 anticorps (C-Term)

N° du produit ABIN2776757

Détail du produit anti-ELAC2 anticorps

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELAC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT

Homologie: Dog: 100%, Human: 100%, Mouse: 83%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against ELAC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ELAC2

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Autre désignation: ELAC2 (ELAC2 Produits)

Synonymes: anticorps 1110017O07Rik, anticorps D11Wsu80e, anticorps Hpc2, anticorps ELC2, anticorps HPC2, anticorps elaC ribonuclease Z 2, anticorps ELAC2, anticorps Elac2

Sujet: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, XPO5, SNX5, ARIH1, TNPO3, WDR4, IPO7, TSN, SARS, PPP2CB, PFDN1, NRD1, HARS, FEN1, FOXH1, SMAD3, SMAD2, COPS5, ASCC2, NDUFA7, GOLM1, CUX1, PUF60,
Protein Size: 501

Poids moléculaire: 55 kDa

ID gène: 60528