ALDOB anticorps (Middle Region)

N° du produit ABIN2776767

Cet anticorps Lapin Polyclonal détecte spécifiquement ALDOB dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval et Mouton.

Aperçu rapide pour ALDOB anticorps (Middle Region) (ABIN2776767)

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDOB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALDOB anticorps

Épitope: Middle Region

Séquence: KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ALDOB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ALDOB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 364 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALDOB

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Autre désignation: ALDOB

Sujet: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13 ) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ALDB, ALDO2
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, MUC20, AGXT2, TXN2, UBC, HIVEP1, ALDOA, APP, HSPA8, ALDOB, ATP6V1E1,
Protein Size: 364

Poids moléculaire: 39 kDa

ID gène: 229

NCBI Accession: NM_000035, NP_000026

UniProt: P05062