CFHR4 anticorps (N-Term)

N° du produit ABIN2776771

Cet anticorps Lapin Polyclonal détecte spécifiquement CFHR4 dans WB. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour CFHR4 anticorps (N-Term) (ABIN2776771)

Antigène: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CFHR4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CFHR4 anticorps

Épitope: N-Term

Fonction: FHR4 Antibody - N-terminal region

Séquence: LWVSCANGQE VKPCDFPEIQ HGGLYYKSLR RLYFPAAAGQ SYSYYCDQNF

Homologie: Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FHR4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FHR4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41371-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CFHR4

Antigène: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Autre désignation: FHR4

Sujet:

Background Information: This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.

Gene Name: complement factor H

Alternative Symbols: FHR4, CFHL4, FHR-4

Protein Name: Complement factor H-related protein 4A EMBL CAG26679.2

Poids moléculaire: 63kDa

ID gène: 10877

NCBI Accession: NP_006675

UniProt: Q5DVJ7