MYBPC3 anticorps (C-Term)
Aperçu rapide pour MYBPC3 anticorps (C-Term) (ABIN2776776)
Antigène
Voir toutes MYBPC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- KGKWVDLSSK VGQHLQLHDS YDRASKVYLF ELHITDAQPA FTGSYRCEVS
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Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against MYBPC3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of human MYBPC3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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Autre désignation
- MYBPC3
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Sujet
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MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Alias Symbols: FHC, CMH4, CMD1MM, LVNC10, MYBP-C
Protein Size: 365 -
Poids moléculaire
- 40 kDa
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ID gène
- 4607
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NCBI Accession
- NM_000256, NP_000247
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UniProt
- Q14896
Antigène
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