DDC anticorps (N-Term)

N° du produit ABIN2776802

L’anticorps Lapin Polyclonal anti-DDC a été validé pour WB et IHC. Il convient pour détecter DDC dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval et Poisson zèbre (Danio rerio). Il y a 1 publication disponible.

Aperçu rapide pour DDC anticorps (N-Term) (ABIN2776802)

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DDC anticorps

Épitope: N-Term

Séquence: EFRRRGKEMV DYVANYMEGI EGRQVYPDVE PGYLRPLIPA AAPQEPDTFE

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 92%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against DDC. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DDC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 480 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DDC (ABIN2776802)

Shimohata, Ishihara, Hattori, Miyamoto, Morishita, Ornthanalai, Raveau, Ebrahim, Amano, Yamada, Sago, Akiba, Mataga, Murphy, Miyakawa, Yamakawa: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." dans: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).

Détails sur DDC

Antigène: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Autre désignation: DDC

Sujet: DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Alias Symbols: AADC
Protein Interaction Partner: ATF6, RELA, AR,
Protein Size: 480

Poids moléculaire: 53 kDa

ID gène: 1644

NCBI Accession: NM_000790, NP_000781

UniProt: P20711

Pathways: Dopaminergic Neurogenesis