DPYS anticorps (N-Term)

N° du produit ABIN2776832

L’anticorps Lapin Polyclonal anti-DPYS a été validé pour WB. Il convient pour détecter DPYS dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye et Porc. Il y a 2+ publications disponibles.

Aperçu rapide pour DPYS anticorps (N-Term) (ABIN2776832)

Antigène: DPYS (Dihydropyrimidinase (DPYS))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DPYS anticorps

Épitope: N-Term

Séquence: VLDAAGKLVL PGGIDTHTHM QFPFMGSRSI DDFHQGTKAA LSGGTTMIID

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against DPYS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DPYS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 519 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DPYS (ABIN2776832)

Thomas, Chen, Lin, Tomlinson, Lam, Liu, Yeung, Chan, Wong: "Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients." dans: Cerebrovascular diseases (Basel, Switzerland), Vol. 25, Issue 3, pp. 261-7, (2008) (PubMed).

Thomas, Ezzeldin, Guarcello, Mattison, Fridley, Diasio: "Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism." dans: Pharmacogenetics and genomics, Vol. 18, Issue 1, pp. 25-35, (2008) (PubMed).

Détails sur DPYS

Antigène: DPYS (Dihydropyrimidinase (DPYS))

Autre désignation: DPYS

Sujet: Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Alias Symbols: DHP, DHPase
Protein Interaction Partner: DPYSL5,
Protein Size: 519

Poids moléculaire: 56 kDa

ID gène: 1807

NCBI Accession: NM_001385, NP_001376

UniProt: Q14117