CKMT2 anticorps (N-Term)

N° du produit ABIN2776839

Cet anticorps Lapin Polyclonal détecte spécifiquement CKMT2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio) et Cobaye. Il a été cité dans 2+ publications.

Aperçu rapide pour CKMT2 anticorps (N-Term) (ABIN2776839)

Antigène: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CKMT2 anticorps

Épitope: N-Term

Fonction: CKMT2 Antibody - N-terminal region

Séquence: GTSVLTTGYL LNRQKVCAEV REQPRLFPPS ADYPDLRKHN NCMAECLTPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CKMT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CKMT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098008

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CKMT2 (ABIN2776839)

Choudhuri, Maitra, Evans: "Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 24, pp. 9818-23, (2013) (PubMed).

Guerrero, Wuyam, Mezin, Vivodtzev, Vendelin, Borel, Hacini, Chavanon, Imbeaud, Saks, Pison: "Functional coupling of adenine nucleotide translocase and mitochondrial creatine kinase is enhanced after exercise training in lung transplant skeletal muscle." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 289, Issue 4, pp. R1144-54, (2005) (PubMed).

Détails sur CKMT2

Antigène: CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))

Autre désignation: CKMT2

Sujet:

Background Information: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.

Gene Name: Creatine kinase, mitochondrial 2 (sarcomeric)

Alternative Symbols: SMTCK

Protein Name: Creatine kinase S-type, mitochondrial

Poids moléculaire: 46kDa

ID gène: 1160

NCBI Accession: NP_001816

UniProt: P17540