GPX3 anticorps (N-Term)

N° du produit ABIN2776848

Cet anticorps Lapin Polyclonal détecte spécifiquement GPX3 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Porc, Boeuf (Vache) et Cobaye.Il a été cité dans 1 publication.

Aperçu rapide pour GPX3 anticorps (N-Term) (ABIN2776848)

Antigène: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPX3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GPX3 anticorps

Épitope: N-Term

Fonction: GPX3 Antibody - N-terminal region

Séquence: DCHGGISGTI YEYGALTIDG EEYIPFKQYA GKYVLFVNVA SYUGLTGQYI

Homologie: Cow: 100%, Dog: 83%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GPX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GPX3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41491-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GPX3 (ABIN2776848)

Maccarrone, Ditzen, Yassouridis, Rewerts, Uhr, Uhlen, Holsboer, Turck: "Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters." dans: Journal of psychiatric research, Vol. 47, Issue 11, pp. 1572-80, (2013) (PubMed).

Détails sur GPX3

Antigène: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Autre désignation: GPX3

Sujet:

Background Information: GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination.Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.

Gene Name: Glutathione peroxidase 3 (plasma)

Alternative Symbols: GPx-P, GSHPx-3, GSHPx-P

Protein Name: Glutathione peroxidase 3

Poids moléculaire: 26 kDa

ID gène: 2878

NCBI Accession: NP_002075

UniProt: P22352

Pathways: Thyroid Hormone Synthesis