HMGCS2 anticorps (N-Term)

N° du produit ABIN2776880

Détail du produit anti-HMGCS2 anticorps

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye, Chévre, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGCS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: PKDVGILALE VYFPAQYVDQ TDLEKYNNVE AGKYTVGLGQ TRMGFCSVQE

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HMGCS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGCS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 508 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HMGCS2 (ABIN2776880)

Clara, Schumacher, Ramachandran, Fedele, Krieger, Langhans, Mansouri: "Metabolic Adaptation of the Small Intestine to Short- and Medium-Term High-Fat Diet Exposure." dans: Journal of cellular physiology, Vol. 232, Issue 1, pp. 167-75, (2016) (PubMed).

Karimian Azari, Leitner, Jaggi, Langhans, Mansouri: "Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-? agonist Wy-14643 in high-fat diet fed rats." dans: PLoS ONE, Vol. 8, Issue 9, pp. e74869, (2013) (PubMed).

Détails sur HMGCS2

Antigène: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Autre désignation: HMGCS2 (HMGCS2 Produits)

Synonymes: anticorps 1300002P16, anticorps mHS, anticorps DDBDRAFT_0219349, anticorps DDBDRAFT_0219924, anticorps DDB_0219349, anticorps DDB_0219924, anticorps Hmgcs1, anticorps Mt3h3mg, anticorps hmgCoA, anticorps 3-hydroxy-3-methylglutaryl-CoA synthase 2, anticorps 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2, anticorps hydroxymethylglutaryl-CoA synthase, anticorps hydroxymethylglutaryl-coa synthase, anticorps 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2, anticorps HMGCS2, anticorps Hmgcs2, anticorps mvaS, anticorps CNC05080, anticorps HMCS1, anticorps hgsA, anticorps MFER_RS00425, anticorps LOC100285783, anticorps ECU10_0510, anticorps Eint_100450

Sujet: HMGCS2 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Protein Interaction Partner: UBC, APP, YWHAQ,
Protein Size: 508

Poids moléculaire: 56 kDa

ID gène: 3158

NCBI Accession: NM_005518, NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha