Hepcidin anticorps (N-Term)

N° du produit ABIN2776909

Cet anticorps Lapin Polyclonal détecte spécifiquement Hepcidin dans WB. Il présente une réactivité envers Humain et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour Hepcidin anticorps (N-Term) (ABIN2776909)

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Hepcidin anticorps

Épitope: N-Term

Séquence: MALSSQIWAA CLLLLLLLAS LTSGSVFPQQ TGQLAELQPQ DRAGARASWM

Homologie: Human: 100%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against HAMP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HAMP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 84 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Hepcidin (ABIN2776909)

Theurl, Theurl, Seifert, Mair, Nairz, Rumpold, Zoller, Bellmann-Weiler, Niederegger, Talasz, Weiss: "Autocrine formation of hepcidin induces iron retention in human monocytes." dans: Blood, Vol. 111, Issue 4, pp. 2392-9, (2008) (PubMed).

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: HAMP

Sujet: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature p
Alias Symbols: HEPC, HFE2B, LEAP-1, LEAP1, PLTR
Protein Interaction Partner: CKAP4, VKORC1, SLC40A1,
Protein Size: 84

Poids moléculaire: 9 kDa

ID gène: 57817

NCBI Accession: NM_021175, NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis