Hepcidin anticorps (N-Term)
Aperçu rapide pour Hepcidin anticorps (N-Term) (ABIN2776909)
Antigène
Voir toutes Hepcidin (HAMP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- HAMP Antibody - N-terminal region
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Séquence
- MALSSQIWAA CLLLLLLLAS LTSGSVFPQQ TGQLAELQPQ DRAGARASWM
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Homologie
- Human: 100%, Rat: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against HAMP. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HAMP
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41620-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Autocrine formation of hepcidin induces iron retention in human monocytes." dans: Blood, Vol. 111, Issue 4, pp. 2392-9, (2008) (PubMed).
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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Autre désignation
- HAMP
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Sujet
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Background Information: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature p
Gene Name: Hepcidin antimicrobial peptide
Alternative Symbols: HEPC, PLTR, HFE2B, LEAP1
Protein Name: Hepcidin
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Poids moléculaire
- 9kDa
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ID gène
- 57817
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NCBI Accession
- NP_066998
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UniProt
- P81172
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Pathways
- Hormone Activity, Transition Metal Ion Homeostasis
Antigène
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