Cardiac Troponin T2 anticorps (N-Term)

N° du produit ABIN2776953

Cet anticorps Lapin Polyclonal détecte spécifiquement Cardiac Troponin T2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour Cardiac Troponin T2 anticorps (N-Term) (ABIN2776953)

Antigène: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cardiac Troponin T2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cardiac Troponin T2 anticorps

Épitope: N-Term

Séquence: ESKPKPRSFM PNLVPPKIPD GERVDFDDIH RKRMEKDLNE LQALIEAHFE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNNT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 295 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cardiac Troponin T2

Antigène: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Autre désignation: TNNT2

Sujet: TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Alias Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6
Protein Interaction Partner: MORF4L2, KDM1A, APP, TNNI1, TNNC1, UBC, TNNI3, MAP3K5, TPM1, PRKCA,
Protein Size: 295

Poids moléculaire: 35 kDa

ID gène: 7139

NCBI Accession: NM_000364, NP_000355

UniProt: A2TDB9