Amylin/DAP anticorps (N-Term)

N° du produit ABIN2776959

Cet anticorps anti-Amylin/DAP Polyclonal Lapin (ABIN2776959) détecte spécifiquement Amylin/DAP dans WB. L’anticorps est réactif avec des échantillons de Humain, Lapin, Chien, Boeuf (Vache) et Cheval.

Aperçu rapide pour Amylin/DAP anticorps (N-Term) (ABIN2776959)

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivité: Humain, Lapin, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amylin/DAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Amylin/DAP anticorps

Épitope: N-Term

Fonction: IAPP Antibody - N-terminal region

Séquence: MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV

Homologie: Cow: 82%, Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IAPP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human IAPP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41728-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Amylin/DAP

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Autre désignation: IAPP

Sujet:

Background Information: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Gene Name: Islet amyloid polypeptide

Alternative Symbols: DAP, IAP

Protein Name: Islet amyloid polypeptide

Poids moléculaire: 4kDa

ID gène: 3375

NCBI Accession: NP_000406

UniProt: P10997

Pathways: Hormone Activity, Feeding Behaviour