Keratin 10 anticorps (N-Term)
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- Antigène Voir toutes Keratin 10 (KRT10) Anticorps
- Keratin 10 (KRT10)
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Porc, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Keratin 10 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EKVTMQNLND RLASYLDKVR ALEESNYELE GKIKEWYEKH GNSHQGEPRD
- Homologie
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against KRT10. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human KRT10
- Top Product
- Discover our top product KRT10 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 584 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Mild recessive bullous congenital ichthyosiform erythroderma due to a previously unidentified homozygous keratin 10 nonsense mutation." dans: The Journal of investigative dermatology, Vol. 128, Issue 7, pp. 1648-52, (2008) (PubMed).
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Mild recessive bullous congenital ichthyosiform erythroderma due to a previously unidentified homozygous keratin 10 nonsense mutation." dans: The Journal of investigative dermatology, Vol. 128, Issue 7, pp. 1648-52, (2008) (PubMed).
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- Antigène
- Keratin 10 (KRT10)
- Autre désignation
- KRT10 (KRT10 Produits)
- Synonymes
- anticorps BCIE, anticorps BIE, anticorps CK10, anticorps EHK, anticorps K10, anticorps KPP, anticorps D130054E02Rik, anticorps K1C1, anticorps Krt-1.10, anticorps Krt1-10, anticorps Ka10, anticorps Ker10, anticorps KRT10, anticorps KRT25, anticorps KRT27, anticorps KRT28, anticorps keratin 10, anticorps keratin 10, type I S homeolog, anticorps keratin, type I cytoskeletal 25, anticorps KRT10, anticorps Krt10, anticorps krt10.S, anticorps LOC101085587
- Sujet
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KRT10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in the gene encoding KRT10 are associated with epidermolytic hyperkeratosis. This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK10, K10, KPP, BIE, EHK, BCIE
Protein Interaction Partner: UBC, Fbxl16, ADRB2, PAN2, Nphp4, Iqcb1, Cep290, Nphp1, Invs, VCAM1, SRC, ITGA4, FN1, ALB, MAGOH, TRAF3IP1, EIF4A3, AHNAK2, KRT2, KRT1, ELAVL1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, NEDD8, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CU
Protein Size: 584 - Poids moléculaire
- 59 kDa
- ID gène
- 3858
- NCBI Accession
- NM_000421, NP_000412
- UniProt
- P13645
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