Keratin 2 anticorps (Middle Region)

N° du produit ABIN2776963

L’anticorps Lapin Polyclonal anti-Keratin 2 a été validé pour WB et IHC. Il convient pour détecter Keratin 2 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Porc et Lapin.

Aperçu rapide pour Keratin 2 anticorps (Middle Region) (ABIN2776963)

Antigène: Keratin 2 (KRT2)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Keratin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Keratin 2 anticorps

Épitope: Middle Region

Séquence: EVKAQYEEIA QRSKEEAEAL YHSKYEELQV TVGRHGDSLK EIKIEISELN

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 81%

Attributs du produit: This is a rabbit polyclonal antibody against KRT2A. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KRT2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 639 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Keratin 2

Antigène: Keratin 2 (KRT2)

Autre désignation: KRT2A

Sujet: KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: KRT2E, KRTE, K2e, CK-2e, KRT2A
Protein Interaction Partner: KRT40, KRT38, KRT31, KRT19, KRT13, Fbxl16, LGR4, EED, ADRB2, PAN2, Nphp4, IQCB1, VCAM1, UBC, FN1, EIF4A3, MAGOH, KRT10, KRT1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5,
Protein Size: 639

Poids moléculaire: 70 kDa

ID gène: 3849

NCBI Accession: NM_000423, NP_000414

UniProt: P35908