Keratin 2 anticorps (Middle Region)

N° du produit ABIN2776963

L’anticorps anti-Keratin 2 Polyclonal Lapin est utilisé pour la détection de Keratin 2 dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Porc et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour Keratin 2 anticorps (Middle Region) (ABIN2776963)

Antigène: Keratin 2 (KRT2)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Keratin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Keratin 2 anticorps

Épitope: Middle Region

Fonction: KRT2A Antibody - middle region

Séquence: EVKAQYEEIA QRSKEEAEAL YHSKYEELQV TVGRHGDSLK EIKIEISELN

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 81%

Attributs du produit: This is a rabbit polyclonal antibody against KRT2A. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KRT2A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41735-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Keratin 2

Antigène: Keratin 2 (KRT2)

Autre désignation: KRT2A

Sujet:

Background Information: KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: Keratin 2

Alternative Symbols: K2e, KRTE, CK-2e, KRT2A, KRT2E

Protein Name: Keratin, type II cytoskeletal 2 epidermal

Poids moléculaire: 65 kDa

ID gène: 3849

NCBI Accession: NP_000414

UniProt: P35908