FGA anticorps (N-Term)

N° du produit ABIN2776977

Cet anticorps anti-FGA Polyclonal Lapin (ABIN2776977) détecte spécifiquement FGA dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chévre, Porc, Mouton, Chien et Cheval.

Aperçu rapide pour FGA anticorps (N-Term) (ABIN2776977)

Antigène: FGA (Fibrinogen alpha Chain (FGA))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chévre, Porc, Mouton, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FGA anticorps

Épitope: N-Term

Fonction: FGA Antibody - N-terminal region

Séquence: MFSMRIVCLV LSVVGTAWTA DSGEGDFLAE GGGVRGPRVV ERHQSACKDS

Homologie: Cow: 93%, Dog: 86%, Goat: 91%, Horse: 85%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 91%, Sheep: 91%

Attributs du produit: This is a rabbit polyclonal antibody against FGA. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FGA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100620

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FGA

Antigène: FGA (Fibrinogen alpha Chain (FGA))

Autre désignation: FGA

Sujet:

Background Information: FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis.The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.

Gene Name: Fibrinogen alpha chain

Alternative Symbols: Fib2

Protein Name: Fibrinogen alpha chain

Poids moléculaire: 71kDa

ID gène: 2243

NCBI Accession: NP_068657

UniProt: Q4QQH7