GHRHR anticorps (N-Term)

N° du produit ABIN2777008

Détail du produit anti-GHRHR anticorps

Antigène: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Épitope: N-Term

Reactivité: Humain, Rat, Porc, Boeuf (Vache), Mouton, Chien, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GHRHR est non-conjugé

Application: Western Blotting (WB)

Séquence: VTLPCPDFFS HFSSESGAVK RDCTITGWSE PFPPYPVACP VPLELLAEEE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 93%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GHRHR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GHRHR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 423 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GHRHR

Antigène: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Autre désignation: GHRHR (GHRHR Produits)

Synonymes: anticorps GHRFR, anticorps GRFR, anticorps IGHD1B, anticorps Ghrfr, anticorps lit, anticorps little, anticorps GHRHREC, anticorps GHRH-R, anticorps growth hormone releasing hormone receptor, anticorps GHRHR, anticorps Ghrhr

Sujet: GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.This This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.
Alias Symbols: GHRFR, GHRHRpsv, GRFR, IGHD1B
Protein Interaction Partner: GHRH, GHRL, MLNR,
Protein Size: 423

Poids moléculaire: 47 kDa

ID gène: 2692

NCBI Accession: NM_000823, NP_000814

UniProt: Q02643

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process