ALAS2 anticorps (N-Term)

N° du produit ABIN2777049

Cet anticorps Lapin Polyclonal détecte spécifiquement ALAS2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye et Cheval.

Aperçu rapide pour ALAS2 anticorps (N-Term) (ABIN2777049)

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ALAS2 anticorps

Épitope: N-Term

Fonction: ALAS2 Antibody - N-terminal region

Séquence: VFKTVNRWAD AYPFAQHFSE ASVASKDVSV WCSNDYLGMS RHPQVLQATQ

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094542

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALAS2

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Autre désignation: ALAS2

Sujet:

Background Information: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Aminolevulinate, delta-, synthase 2

Alternative Symbols: ASB, ANH1, XLSA, ALASE, XLDPP, XLEPP, ALAS-E, SIDBA1

Poids moléculaire: 57kDa

ID gène: 212

NCBI Accession: NP_001033058

UniProt: P22557

Pathways: Transition Metal Ion Homeostasis