TNNI1 anticorps (N-Term)

N° du produit ABIN2777151

Détail du produit anti-TNNI1 anticorps

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chévre, Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 187 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TNNI1 (ABIN2777151)

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." dans: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Détails sur TNNI1

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Autre désignation: TNNI1 (TNNI1 Produits)

Synonymes: anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TnI-S4, anticorps SSTNI, anticorps TNN1, anticorps 2700018B22Rik, anticorps AI747285, anticorps ssTnI, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps troponin 1, anticorps zgc:86895, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin I, skeletal, slow 1, anticorps troponin T1, skeletal, slow, anticorps troponin I1, slow skeletal type S homeolog, anticorps troponin I type 1 (skeletal, slow), anticorps troponin I4b, tandem duplicate 2, anticorps TNNT1, anticorps TNNI1, anticorps Tnni1, anticorps Tnnt1, anticorps tnni1.S, anticorps tnni4b.2

Sujet: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Alias Symbols: DKFZp451O223, TNN1, SSTNI
Protein Interaction Partner: PNMA1, MDFI, TRIM63, TRIM55, TNNC1, TNNT2, EIF3I, CCDC85B, TNNT1, ACTA1, PKD2L1,
Protein Size: 187

Poids moléculaire: 21 kDa

ID gène: 7135

NCBI Accession: NM_003281, NP_003272

UniProt: P19237