TNNI1 anticorps (N-Term)

N° du produit ABIN2777151

Il existe 1 publication pour ce produit. L’anticorps anti-TNNI1 Polyclonal Lapin est utilisé pour la détection de TNNI1 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour TNNI1 anticorps (N-Term) (ABIN2777151)

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TNNI1 anticorps

Épitope: N-Term

Fonction: TNNI1 Antibody - N-terminal region

Séquence: MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111874

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TNNI1 (ABIN2777151)

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." dans: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Détails sur TNNI1

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Autre désignation: TNNI1

Sujet:

Background Information: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

Gene Name: Troponin I type 1 (skeletal, slow)

Alternative Symbols: TNN1, SSTNI

Protein Name: Troponin I, slow skeletal muscle

Poids moléculaire: 21kDa

ID gène: 7135

NCBI Accession: NP_003272

UniProt: P19237