NFIL3 anticorps (Middle Region)

N° du produit ABIN2777219

Détail du produit anti-NFIL3 anticorps

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFIL3 est non-conjugé

Application: Western Blotting (WB)

Séquence: GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NFIL3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 462 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFIL3

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Autre désignation: NFIL3 (NFIL3 Produits)

Synonymes: anticorps e4bp4, anticorps il3bp1, anticorps nfil3a, anticorps nf-il3a, anticorps MGC107826, anticorps NFIL3, anticorps E4BP4, anticorps IL3BP1, anticorps NF-IL3A, anticorps NFIL3A, anticorps E4BP4-1, anticorps zgc:100867, anticorps AV225605, anticorps nuclear factor, interleukin 3 regulated, anticorps nuclear factor, interleukin 3 regulated L homeolog, anticorps nuclear factor, interleukin 3, regulated, anticorps nfil3, anticorps NFIL3, anticorps Nfil3, anticorps nfil3.L

Sujet: NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
Protein Size: 462

Poids moléculaire: 51 kDa

ID gène: 4783

NCBI Accession: NM_005384, NP_005375

UniProt: Q16649