IRF8 anticorps (C-Term)

N° du produit ABIN2777225

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF8 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Porc et a été mentionné dans 1 publication.

Aperçu rapide pour IRF8 anticorps (C-Term) (ABIN2777225)

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF8 anticorps

Épitope: C-Term

Séquence: QLAEEAGKSC GAGSVMQAPE EPPPDQVFRM FPDICASHQR SFFRENQQIT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against IRF8. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 426 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IRF8 (ABIN2777225)

Ye, Wang, Wang, Wang, Song, Hou, Zhou, Li, Ho: "CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes." dans: Hepatology (Baltimore, Md.), Vol. 49, Issue 3, pp. 753-62, (2009) (PubMed).

Détails sur IRF8

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Autre désignation: IRF8

Sujet: Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
Alias Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8
Protein Interaction Partner: SPI1, IRF1, TOP1, ZBTB17, PDGFRB, CBL, UBC, COPS4, COPS5, COPS6, COPS2, MID1, IRF6, GPS1, CDK4, SQSTM1, TRAF6, SMURF2, IRF2, TRIM21, IRF8, ETV6, RELA, NFKB1,
Protein Size: 426

Poids moléculaire: 48 kDa

ID gène: 3394

NCBI Accession: NM_002163, NP_002154

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin