NFE2 anticorps (N-Term)

N° du produit ABIN2777230

Cet anticorps anti-NFE2 est un anticorps Lapin Polyclonal détectant NFE2 dans WB. Adapté pour Humain, Souris, Rat, Cheval, Boeuf (Vache) et Cobaye.

Aperçu rapide pour NFE2 anticorps (N-Term) (ABIN2777230)

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFE2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NFE2 anticorps

Épitope: N-Term

Séquence: MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP

Homologie: Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 373 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFE2

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Autre désignation: NFE2

Sujet: NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: NF-E2, p45
Protein Interaction Partner: BTRC, NFE2L3, NFE2L2, NFE2, ATF4, Dlg4, TXN, ITCH, Yap1, Nedd4, WWP1, MAPK8, KAT2B, SCAND1, SSX5, HMGN1, ELF5, PHYHIP, MAFF, MAFG, PEX14, MAFK, CREBBP,
Protein Size: 373

Poids moléculaire: 41 kDa

ID gène: 4778

NCBI Accession: NM_006163, NP_006154

UniProt: Q16621