NFE2 anticorps (N-Term)

N° du produit ABIN2777230

Cet anticorps anti-NFE2 Polyclonal Lapin (ABIN2777230) détecte spécifiquement NFE2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache) et Cobaye.

Aperçu rapide pour NFE2 anticorps (N-Term) (ABIN2777230)

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFE2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NFE2 anticorps

Épitope: N-Term

Fonction: NFE2 Antibody - N-terminal region

Séquence: MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP

Homologie: Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31217-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFE2

Antigène: NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))

Autre désignation: NFE2

Sujet:

Background Information: NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Gene Name: Nuclear factor (erythroid-derived 2), 45 kDa

Alternative Symbols: p45, NF-E2

Protein Name: Transcription factor NF-E2 45 kDa subunit

Poids moléculaire: 41kDa

ID gène: 4778

NCBI Accession: NP_006154

UniProt: Q16621