NFE2 anticorps (N-Term)
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- Antigène Voir toutes NFE2 Anticorps
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFE2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP
- Homologie
- Cow: 92%, Guinea Pig: 87%, Horse: 87%, Human: 100%, Mouse: 77%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFE2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFE2
- Top Product
- Discover our top product NFE2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 373 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
- Autre désignation
- NFE2 (NFE2 Produits)
- Sujet
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NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: NF-E2, p45
Protein Interaction Partner: BTRC, NFE2L3, NFE2L2, NFE2, ATF4, Dlg4, TXN, ITCH, Yap1, Nedd4, WWP1, MAPK8, KAT2B, SCAND1, SSX5, HMGN1, ELF5, PHYHIP, MAFF, MAFG, PEX14, MAFK, CREBBP,
Protein Size: 373 - Poids moléculaire
- 41 kDa
- ID gène
- 4778
- NCBI Accession
- NM_006163, NP_006154
- UniProt
- Q16621
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