Retinoic Acid Receptor beta anticorps (N-Term)

N° du produit ABIN2777235

Cet anticorps Lapin Polyclonal détecte spécifiquement Retinoic Acid Receptor beta dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour Retinoic Acid Receptor beta anticorps (N-Term) (ABIN2777235)

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor beta est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Retinoic Acid Receptor beta anticorps

Épitope: N-Term

Séquence: EKALKACFSG LTQTEWQHRH TAQSIETQST SSEELVPSPP SPLPPPRVYK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against RARB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RARB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Retinoic Acid Receptor beta

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Autre désignation: RARB

Sujet: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.
Protein Interaction Partner: RXRG, RXRB, MEOX2, ITGB1BP2, PRKD2, SMAD2, CCNH, HACE1, PNRC1, NCOR2, EIF3I, NCOA1, MAP6, SRC, RXRA, HR, GATA3, NCOA3, CEBPB, CEBPA, NR4A2, DNMT3B, DNMT3A, DNMT1, HIST4H4, HDAC1,
Protein Size: 448

Poids moléculaire: 49 kDa

ID gène: 5915

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway