NFYA anticorps (C-Term)

N° du produit ABIN2777243

L’anticorps Lapin Polyclonal anti-NFYA a été validé pour WB et IHC. Il convient pour détecter NFYA dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour NFYA anticorps (C-Term) (ABIN2777243)

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFYA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NFYA anticorps

Épitope: C-Term

Séquence: YLHESRHRHA MARKRGEGGR FFSPKEKDSP HMQDPNQADE EAMTQIIRVS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%

Attributs du produit: This is a rabbit polyclonal antibody against NFYA. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 347 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFYA

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Autre désignation: NFYA

Sujet: NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Alias Symbols: HAP2, CBF-A, CBF-B, NF-YA
Protein Interaction Partner: LUC7L2, POGZ, NFYB, GTF2A1, CSNK2A1, UBC, APPBP2, TP63, TP53, NFYC, EP300, CDK2, CCNA2, CDC25A, APP, RPS6KA6, JUN, HDAC1, ATF2, SP1, TAF6, TAF11, TAF12, PAPOLG, PWP1, SREBF2, ZHX2, ZHX1, ZHX3, KPNB1, SRSF1, HMGA1, SRF, USF2, USF1, NFYA, NR5A1, POU2F1, CEB
Protein Size: 347

Poids moléculaire: 37 kDa

ID gène: 4800

NCBI Accession: NM_002505, NP_002496

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha