HOXD4 anticorps (C-Term)

N° du produit ABIN2777273

Cet anticorps anti-HOXD4 est un anticorps Lapin Polyclonal détectant HOXD4 dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Porc et Cheval.

Aperçu rapide pour HOXD4 anticorps (C-Term) (ABIN2777273)

Antigène: HOXD4 (Homeobox D4 (HOXD4))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXD4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HOXD4 anticorps

Épitope: C-Term

Séquence: RMKWKKDHKL PNTKGRSSSS SSSSSCSSSV APSQHLQPMA KDHHTDLTTL

Homologie: Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HOXD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HOXD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 255 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HOXD4

Antigène: HOXD4 (Homeobox D4 (HOXD4))

Autre désignation: HOXD4

Sujet: HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
Alias Symbols: HOX4, HOX4B, HHO.C13, HOX-5.1, Hox-4.2
Protein Interaction Partner: EP300, CREBBP, TIGD4, ASB8, ZSCAN18, CNOT7, ZBTB32, RNPS1, ZMYND11, HOXB13, DEDD, SNAI1, RXRG, HNRNPAB, ETV4, PBX1, HIPK1, MEIS1, XRCC6,
Protein Size: 255

Poids moléculaire: 28 kDa

ID gène: 3233

NCBI Accession: NM_014621, NP_055436

UniProt: P09016