Msx2/Hox8 anticorps (N-Term)

N° du produit ABIN2777276

Détail du produit anti-Msx2/Hox8 anticorps

Antigène: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Msx2/Hox8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 91%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 267 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Msx2/Hox8

Antigène: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Autre désignation: MSX2 (Msx2 Produits)

Synonymes: anticorps CRS2, anticorps FPP, anticorps HOX8, anticorps MSH, anticorps PFM, anticorps PFM1, anticorps BB122635, anticorps Hox-8, anticorps Hox8, anticorps Hox8.1, anticorps HOX-8, anticorps Msx-2, anticorps msh homeobox 2, anticorps MSX2, anticorps Msx2

Sujet: MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRS2, FPP, HOX8, MSH, PFM, PFM1
Protein Interaction Partner: ATXN1, PIAS2, UBC, XRCC5, XRCC6, ZDHHC2, TLE2, TLE1, PPARG, POU2AF1, NR3C1, POLR3D, SPEN, ZBTB17, RUNX2, DLX5, MAGED1, GTF2F2, GTF2F1, MSX1, DLX2, MSX2, CEBPA, PITX2,
Protein Size: 267

Poids moléculaire: 29 kDa

ID gène: 4488

NCBI Accession: NM_002449, NP_002440

UniProt: P35548