HOXA5 anticorps (Middle Region)

N° du produit ABIN2777305

Cet anticorps anti-HOXA5 est un anticorps Lapin Polyclonal détectant HOXA5 dans WB et IHC. Adapté pour Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien et Cheval. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour HOXA5 anticorps (Middle Region) (ABIN2777305)

Antigène: HOXA5 (Homeobox A5 (HOXA5))

Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXA5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HOXA5 anticorps

Épitope: Middle Region

Séquence: VGTASGAEED APASSEQASA QSEPSPAPPA QPQIYPWMRK LHISHDNIGG

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HOXA5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 270 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HOXA5 (ABIN2777305)

Heshmati, Kharazi, Türköz, Chang, Kamali Dolatabadi, Boström, Krstic, Boukoura, Wagner, Kadri, Månsson, Altun, Qian, Walfridsson: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." dans: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).

Boucherat, Montaron, Bérubé-Simard, Aubin, Philippidou, Wellik, Dasen, Jeannotte: "Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 304, Issue 12, pp. L817-30, (2013) (PubMed).

Détails sur HOXA5

Antigène: HOXA5 (Homeobox A5 (HOXA5))

Autre désignation: HOXA5

Sujet: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
Alias Symbols: HOX1, HOX1.3, HOX1C, MGC9376
Protein Interaction Partner: PRMT6, TWIST1, UBC, ELAVL1, SOX2, ZNF408, GTF2A1L, SMAD1, DDIT3, PBX1, MEIS1, FOXA2, CDX4, FOXO1,
Protein Size: 270

Poids moléculaire: 29 kDa

ID gène: 3202

NCBI Accession: NM_019102, NP_061975

UniProt: Q6FG31