HDAC6 anticorps (N-Term)

N° du produit ABIN2777306

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC6 dans WB, IHC et ChIP. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Lapin, Chien, Cobaye, Boeuf (Vache) et Cheval.

Aperçu rapide pour HDAC6 anticorps (N-Term) (ABIN2777306)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain, Souris, Rat, Porc, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-HDAC6 anticorps

Épitope: N-Term

Séquence: VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1215 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: HSP90B1, ACTB, UBC, TRIM50, MYH10, DYNC1H1, DDIT3, ELAVL1, MAPK3, MAPK1, RUNX2, TUBA1B, SUMO1, RANBP9, NEDD8, ADRB2, ATXN3, MEF2B, SQSTM1, HSP90AA1, RASSF2, SLMAP, SAV1, CTTNBP2NL, BAG3, SETD8, TUBB, HSPA8, HSPA6, HSPA5, HSPA4, HSPA2, HSPA1L, DNAJA1, ETV6
Protein Size: 1215

Poids moléculaire: 131 kDa, 17 kDa

ID gène: 10013

NCBI Accession: NM_006044

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling