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HDAC6 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC6 dans WB, IHC et ChIP. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Lapin, Chien, Cobaye, Boeuf (Vache) et Cheval.
N° du produit ABIN2777306
534,11 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour HDAC6 anticorps (N-Term) (ABIN2777306)

Antigène

Voir toutes HDAC6 Anticorps
HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité

  • 151
  • 55
  • 27
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Porc, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval

Hôte

  • 133
  • 24
  • 1
Lapin

Clonalité

  • 115
  • 43
Polyclonal

Conjugué

  • 83
  • 10
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HDAC6 est non-conjugé

Application

  • 118
  • 66
  • 47
  • 32
  • 29
  • 26
  • 26
  • 23
  • 21
  • 17
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
  • Épitope

    • 27
    • 19
    • 15
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Fonction

    HDAC6 Antibody - N-terminal region

    Séquence

    VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

    Attributs du produit

    This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102606

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    prevent freeze-thaw cycles

    Stock

    4 °C,-20 °C

    Stockage commentaire

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    Autre désignation

    HDAC6

    Sujet

    Background Information: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

    Gene Name: Histone deacetylase 6

    Alternative Symbols: HD6, JM21, CPBHM, PPP1R90

    Protein Name: HDAC6 protein EMBL AAH05872.1

    Poids moléculaire

    131kDa, 17 kD

    ID gène

    10013

    UniProt

    Q9UBN7

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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