SUPT16H anticorps (N-Term)
Aperçu rapide pour SUPT16H anticorps (N-Term) (ABIN2777339)
Antigène
Voir toutes SUPT16H AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- ASKKKVEFLK QIANTKGNEN ANGAPAITLL IREKNESNKS SFDKMIEAIK
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against SUPT16H. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SUPT16H
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 602 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Autre désignation
- SUPT16H
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Sujet
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Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.
Alias Symbols: CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Protein Interaction Partner: HIST1H2AB, UBC, SUMO2, ATRX, SUMO1, NEDD8, RNF20, PAF1, EED, RNF2, BMI1, rev, FTH1, QRICH1, SRPK2, ICAM1, CD81, IGSF8, PNKP, VCP, FMNL1, SSRP1, ESR1, CENPA, LEO1, RBM25, PRPF6, NCSTN, RTF1, ACIN1, PSIP1, USP39, PRPF8, SF3A1, SAP18, CTR9, DDX21, PRPF3, PRP
Protein Size: 602 -
Poids moléculaire
- 66 kDa
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ID gène
- 11198
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NCBI Accession
- NM_007192
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UniProt
- Q9Y5B9
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Pathways
- Chromatin Binding
Antigène
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