DLX4 anticorps (Middle Region)

N° du produit ABIN2777375

Détail du produit anti-DLX4 anticorps

Antigène: DLX4 (Distal-Less Homeobox 4 (DLX4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLX4 est non-conjugé

Application: Western Blotting (WB)

Séquence: CQQPAALSQP LCGPAEHPQE LEADSEKPRL SPEPSERRPQ APAKKLRKPR

Homologie: Human: 100%, Mouse: 90%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against DLX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DLX4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 240 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DLX4

Antigène: DLX4 (Distal-Less Homeobox 4 (DLX4))

Autre désignation: DLX4 (DLX4 Produits)

Synonymes: anticorps BP1, anticorps DLX7, anticorps DLX8, anticorps DLX9, anticorps Dlx-4, anticorps Dlx7, anticorps DLX4, anticorps dlx8, anticorps dlx7, anticorps fj03c01, anticorps wu:fj03c01, anticorps zgc:109858, anticorps distal-less homeobox 4, anticorps distal-less homeobox 4a, anticorps distal-less homeobox 4b, anticorps DLX4, anticorps Dlx4, anticorps dlx4a, anticorps dlx4b

Sujet: DLX4 may play a role in determining the production of hemoglobin S. May act as a repressor. Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Alias Symbols: BP1, DLX7, DLX8, DLX9
Protein Interaction Partner: LSM3, MAGED1,
Protein Size: 240

Poids moléculaire: 26 kDa

ID gène: 1748

NCBI Accession: NM_138281, NP_612138

UniProt: Q92988