SLC26A3 anticorps (Middle Region)

N° du produit ABIN2777377

Détail du produit anti-SLC26A3 anticorps

Antigène: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Mouton, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC26A3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: DAVLHILMKK DYSTSKFNPS QEKDGKIDFT INTNGGLRNR VYEVPVETKF

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC26A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC26A3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 764 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC26A3 (ABIN2777377)

Kjærgaard, Damm, Chang, Riis, Rasmussen, Hytting-Andreasen, Krug, Schulzke, Bindslev, Hansen: "Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?" dans: International journal of molecular sciences, Vol. 21, Issue 5, (2020) (PubMed).

Détails sur SLC26A3

Antigène: SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))

Autre désignation: SLC26A3 (SLC26A3 Produits)

Sujet: SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CLD, DRA
Protein Interaction Partner: SLC9A3R1, SLC9A3R2,
Protein Size: 764

Poids moléculaire: 84 kDa

ID gène: 1811

NCBI Accession: NM_000111, NP_000102

UniProt: P40879